Efficacy and safety of Butantan-DV in participants aged 2-59 years through an extended follow-up: results from a double-blind, randomised, placebo-controlled, phase 3, multicentre trial in Brazil

Nogueira ML, et al. Lancet Infect Dis. 2024 Nov;24(11):1234-1244. doi: 10.1016/S1473-3099(24)00376-1. Epub 2024 Aug 5. PMID: 39116904.

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A flow cytometry-based assay to measure neutralizing antibodies against SARS-CoV-2 virus. 

Pscheidt VM, et al. A flow cytometry-based assay to measure neutralizing antibodies against SARS-CoV-2 virus. Cytometry. 2024; 105(6): 446–457. https://doi.org/10.1002/cyto.a.24838

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A high CMV-specific T cell response associates with SARS-CoV-2-specific IL-17 T cell production.

Frozza, F.T.B., Fazolo, T., de Souza, P.O. et al. A high CMV-specific T cell response associates with SARS-CoV-2-specific IL-17 T cell production. Med Microbiol Immunol 212, 75–91 (2023). https://doi.org/10.1007/s00430-022-00758-1

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IL-21 treatment recovers follicular helper T cells and neutralizing antibody production in respiratory syncytial virus infection.

Gassen, R.B., et al (2021), IL-21 treatment recovers follicular helper T cells and neutralizing antibody production in respiratory syncytial virus infection. Immunol. Cell Biol., 99: 309-322. https://doi.org/10.1111/imcb.12418

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Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.

T Fazolo, K Lima, JC Fontoura, PO de Souza, G Hilario, R Zorzetto, L Rodrigues Júnior, VM Pscheidt, JCF Neto, AF Haubert, I Gambin, AC Oliveira, RS Mello, MB Balbe e Gutierres, RB Gassen, LD Coimbra, A Borin, RE Marques, ITS Sartor, GO Zavaglia, IR Fernandes, HI Nakaya, FH Varela, MP Bonatto, TJ Borges, SM Callegari-Jacques, MSC da Costa, JA Schwartz, MC Scotta, RT Stein, and C Bonorino.

Nature Communications 2021

https://www.nature.com/articles/s41467-021-27120-y

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SARS-CoV-2 infected children form early immune memory responses dominated by nucleocapsid-specific CD8+ T cells and antibodies.

K Lima, JC Fontoura, PO de Souza, T Fazolo, G Hilario, R Zorzetto, LC Rodrigues Junior, LD Coimbra, A Borin, K Bispo-dos-Santos, F Granja, RE Marques, GO Zavaglia, IR Fernandes, FH Varela, MP Bonatto, ML Tonini, GM Ikeda do Carmo, WA Ferreira de Almeida, TJ Borges, HI Nakaya, JL Proenca-Modena, SM Callegari-Jacques, MC Scotta, RT Stein, and C Bonorino.

Frontiers in Immunology 2022

https://europepmc.org/article/med/36405692

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Host expression system modulates recombinant Hsp70 activity through post‐translational modifications. 

MM Rigo, TJ Borges, BJ Lang, A Murshid, D Wolfgeher, SK Calderwood, AW Truman, C Bonorino.

The FEBS journal 2020

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/febs.15279

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Comparison of 2D and 3D cell culture models for cell growth, gene expression and drug resistance.

JC Fontoura, C Viezzer, FG dos Santos, RA Ligabue, R Weinlich, RD Puga, D Antonow, P Severino, C Bonorino.

Materials Science and Engineering: C 2020

https://www.sciencedirect.com/science/article/pii/S0928493119305934

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Vaccination with RSV M209-223 peptide promotes a protective immune response associated with reduced pulmonary inflammation.

T Fazolo, RB Gassen, DN de Freitas, TJ Borges, MM Rigo, RD da Silva, F Maito, A Cunha, DAGB Mendes, A Báfica, JE Vargas, APD de Souza, C Bonorino.

Antiviral Research 2018

https://doi.org/10.1016/j.antiviral.2018.07.007

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March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity.

TJ Borges, N Murakami, FD Machado, A Murshid, BJ Lang, RL Lopes, LM Bellan, M Uehara, KH Antunes, MJ Pérez-Saéz, G Birrane, P Vianna, JIB Gonçalves, RF Zanin, J Azzi, R Abdi, S Ishido, JS Shin, APD Souza, SK Calderwood, LV Riella, C Bonorino.

Nature Communications 2018

https://doi.org/10.1038/s41467-018-05572-z

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IL‐21 treatment recovers follicular helper T cells and neutralizing antibody production in respiratory syncytial virus infection.

RB Gassen, T Fazolo, DN Freitas, TJ Borges, K Lima, GL Antunes, F Maito, DAG Bueno Mendes, A Báfica, LC Rodrigues Jr, R Stein, APD de Souza, C Bonorino.

Immunology and Cell Biology 2021

https://onlinelibrary.wiley.com/doi/full/10.1111/imcb.12418

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GRPR antagonist protects from drug‐induced liver injury by impairing neutrophil chemotaxis and motility.

RS Czepielewski, N Jaeger, PE Marques, MM Antunes, MM Rigo, DM Alvarenga, RV Pereira, RD da Silva, TG Lopes, VD da Silva, BN Porto, GB Menezes, C Bonorino.

European Journal of Immunology 2017

https://onlinelibrary.wiley.com/doi/full/10.1002/eji.201646394

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Gastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophils.

RS Czepielewski, BN Porto, LB Rizzo, C Bonorino.

PNAS 2011

https://www.pnas.org/doi/abs/10.1073/pnas.1110996109

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PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways

Y Zhao, CK Lee, C-H Lin, RB Gassen, X Xu, Z Huang, C Xiao, C Bonorino, L-F Lu, JD Bui, E Hui.

Immunity 2019

https://doi.org/10.1016/j.immuni.2019.11.003

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